Autoimmune Disorders in Association with Hairy-Cell Leukaemia

ABSTRACT

Autoimmune diseases in the form of cutaneous leucocytoclastic Vasculitis (CLCV), polyarteritis nodosa (PAN), cerebral arteritis and cryoglobulinemia are uncommon associations of Hairy Cell Leukaemia (HCL). We report a case of a 55 year old male with HCL, carcinomatous meningitis, cryoglobulinemia and cutaneous leukocytoclastic vasculitis, which preceded the diagnosis of HCL, leucocytoclastic vasculitis was confirmed on skin biopsy, the cutaneous lesions regressed on steroid therapy.