Age and Sex Related Changes in Thyroid Functions in Normal Healthy Subjects of Jammu Region.

ABSTRACT

The study was conducted on 150 normal healthy subjects of different age groups of both sexes (belonging to Jammu region only) to find out the pattern of physiological variations in the levels of the thyroid hormones viz. T3 (triiodothyronine), T4 (thyroxine) and TSH (thyroid stimulating hormone). The blood levels of T3, T4 and TSH of these subjects were found out by using radioimmunossay technique. The serum T3 and T4 levels decreased progressively with age with the highest levels being observed in children and lowest in the elderly. The serum T3 levels of males and females did not show any difference in any age group, whereas the mean serum T4 level in the adult females was more than that of adult male though the difference is statistically insignificant. There was, however, no difference between the serum T4 levels of males and females of children, adolescents and elderly groups. The mean serum TSH level was found to increase progressively with age and did not show any significant difference in males and females in any age group.