Bacterial Profile of Blood Stream Infections and Antibiotic Resistance Pattern of Isolates.

ABSTRACT

Blood samples from 2542 clinically diagnosed cases of septicemia were processed. Out of these 946 (76.55%) were from Pediatric Department and rest from other Departments. Growth was obtained in 509(20.02%) cases . Candida spp were isolated from 23 (4.57 ) cases Out of 486 bacterial isolates 52.67 % were gram positive bacteria whereas 47.33% were gram negative bacilli . Staph aureus 133 (27.37%)was the predominant organisms followed by CONS 98 (20.1%). Amongst gram negative organisms Enterobacter 69 (14.19 %) was the most predominant followed by Esch coli 45 (9.27 %) Pseudomonas 37 (7.62 %) and Acinetobacter spp 34 (6.69 %). Amongst gram positive organisms maximum resistance was seen with ampicillin (74.61%) and erythromycin (69.67 %). Most of the gram negative bacilli were MDR (71%). Maximum resistance was observed with ampicillin (86.1% ) cephalexin (68.07%) and piperacillin (57.71%). Most successful drugs were amikacin,gentamicin and cefotaxime. 34.35% of the isolates were ESBL producers.