Study of Prevalence of Uropathogens and Antibiotic Sensitivity Pattern in Diabetic Patients Suffering From Urinary Tract Infection in a Tertiary Care Teaching Hospital.

ABSTRACT

Background: Diabetes Mellitus is a major health problem of today's world and its prevalence is riding day by day. Urinary tract infection is its common complication. Antibiotic resistance against various uropathogens is also increasing day by day. Therefore, this prospective was carried out to know the prevalence of culture positive Urinary Tract Infection in diabetic patients and to find out the pattern of antibiotic sensitivity. Methods: Around 430 diabetic patients with urinary tract infections confirmed from Microbiology department from Oct, 2012 to February, 2014 were enrolled. Results: Out of 430 patients, 302 urine specimens (Male n=140, 46.4%) and (Females n=162, 53.5%) were found to be culture positive. The overall prevalence of urinary tract infection was 70.2% higher in females (53.5%) than males (46.4%). Among the 302 isolates, 256 belongs to gram negative bacilli, 46 were gram positive cocci. In gram negative bacilli, most of the isolates160 (62.3%) were E.coli, and in gram positive cocci, Enterococci (55%) were predominately found. Imipenem was found sensitive for both Gram negative bacilli as well as Gram positive cocci. Conclusion: Diabetics with UTI found with high female/male ratio. Escherichia-coli was most common organism followed by klebsiella, and pseudomonas. Most of the urinary isolates were sensitive to Imipenem, Meropenem, ceftriaxone, whereas resistance was high for Amikacin.