Clinico-Pathological Profile of Patients with Spinal Cord Lesions.

ABSTRACT

Background: Spinal cord is the site of variety of lesions and includes both non neoplastic and neoplastic lesions. Common non neoplastic lesions include meningomyeloceles, dermoid cysts, epidermoid cysts, arachnoid cysts and neurenteric cysts whereas neoplastic lesions include astrocytomas, ependymomas, schwannomas, neurofibromas and meningiomas. The aim is to study clinico-pathological profile of patients with spinal cord lesions. Methods: This was a prospective study conducted at Department of Pathology, Osmania General Hospital, Secunderabad from June 2010 to May 2013. All specimens received during study period. Only samples related to spinal cord were included. Results: Of all, non-neoplastic were 28 cases [43%] and neoplastic were 37 cases [57%]. Males were 30 cases [46%] and females were 35 cases [54%] with slight predominance in females. Of all most common were Meningomyelocele [23%] followed by Schwannomas [19%], Neurofibromas [12%], Lipomeningomyelocele [9%], Ependymomas [6%], Meningiomas [6%], Astrocytomas [5%], Dermoid cyst [5%], Arachnoid cyst [3%], Neurenteric cyst [3%], Teratoma [3%] and others include Paraganglioma, PNET, Oligodendroglioma, Metastatic deposits. Intramedullary lesions constitute 10 cases [19%] with [3 non neoplastic and 7 neoplastic], Intradural extramedullary lesions constitute 24 cases [54%] with [4 non neoplastic and 20 neoplastic], Extradural lesions constitute 31 cases [27%] with [21 non neoplastic and 10 neoplastic]. Conclusion: Most non neoplastic lesions in the spinal cord were due to developmental defects and present in younger age group whereas most neoplastic were acquired and occur in adults.