Oral Lesions in Neurofibromatosis Type I: Report of a Case and Clinical Implications.

ABSTRACT

Neurofi broma is a benign peripheral nerve sheath tumor and one of the most frequent tumors of neural origin. Its presence is one of the main clinical criteria for the diagnosis of neurofi bromatosis Type I (NF-I). NF-I is a hereditary disorder inherited as an autosomal dominant trait and the patients present with skin lesions, i.e., café au lait spots and neurofi bromas. Diagnosis is mainly based on a series of clinical criteria. NF-I may present with defi nite oral lesions, which mandate the dental surgeons with the responsibility of accurate diagnosis. Th e paper emphasizes the role of an oral diagnostician in the recognition of NF-I in a family.