Dermatonecrotic lesions in rabbits caused by neuraminidase.
Article
in English
| IMSEAR
| ID: sea-17661
ABSTRACT
In an attempt to study the role of neuraminidase in cholera vibrio pathogenesis, the dermatonecrotic effect of a purified neuraminidase preparation was studied in rabbits. The experiments demonstrated that dermatonecrotic lesions resulted from intracutaneous injection of a purified neuraminidase preparation (0.5 specific human dose or 1 NU) as well as significant doses of cholera toxoid containing the enzyme (4,12,18 specific human doses).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rabbits
/
Skin
/
Toxoids
/
Female
/
Male
/
Cholera Toxin
/
Injections, Subcutaneous
/
Animals
/
Necrosis
/
Neuraminidase
Language:
English
Year:
1992
Type:
Article
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