Clinical Profile of Neurological Manifestations in HIV-Reactive Patients and Their Relation with CD4 Count.
Article
in English
| IMSEAR
| ID: sea-177753
ABSTRACT
Background:
Neurologic abnormalities have been noted in one-third of patients with AIDS, but at autopsy the nervous system is affected in all of them.Aim:
To study the clinical profile of neurological manifestations in HIV reactive patients and their correlation with CD4 counts.Methods:
A randomized case study was conducted at Department of Medicine, Government Medical College, Patiala over a period of 2 years. 200 HIV-infected adult and adolescent patients (>15 years of age) were studied. The diagnosis of HIV was confirmed by 3 HIV ELISA& RAPID positive reports in symptomatic patients.Results:
In the present study, 37% of the patients were in the age group of 26-35 years. Males are affected more frequently than females, with a male to female sex ratio of 2.56 1. Meningitis, HIV associated dementia, Progressive multifocal leukoencephalopathy& peripheral neuropathy are the commonest neurological disorders observed in HIV-infected patients. Tuberculosis is the commonest opportunistic infection in retroviral positive patients.Conclusion:
Central nervous system infections, intracranial mass lesions, stroke, and HIV-associated dementia are more common in patients with a CD4+ count less than 200.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Controlled clinical trial
Language:
English
Year:
2016
Type:
Article
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