Maternal Age at Childbirth and Perinatal and Under-five Mortality in a Prospective Birth Cohort from Delhi.
Indian Pediatr
;
2016 Oct; 53(10): 871-877
Article
in English
| IMSEAR
| ID: sea-179255
ABSTRACT
Objective:
To evaluate the relationship between maternal age at child birth, and perinatal and under-five mortality.Design:
Prospective birth cohort.Setting:
Urban community.Participants:
9169 pregnancies in the New Delhi Birth Cohort resulted in 8181 live births. These children were followed for survival status and anthropometric measurements at birth (+3 days), 3,6,9 and 12 months (7 days), and every 6 months thereafter until 21 years age. Information on maternal age at child birth and socio-demographic profile was also obtained. Outcomemeasures:
Offspring mortality from 28 weeks gestation till 5 years age.Results:
Offspring mortality (stillbirths – 5 years; n=328) had a U-shaped association with maternal age (P<0.001). Compared to the reference group (20-24 years), younger (£19 years) and older (³ 35 years) maternal ages were associated with a higher risk of offspring mortality (HR 1.68; 95% CI 1.16, 2.43 and HR 1.48; 95% CI 1.01, 2.16, respectively). In young mothers, the increased risk persisted after adjustment for socio-economic confounders (maternal education, household income and wealth; HR 1.51; 95% CI 1.03, 2.20) and further for additional behavioral (place of delivery) and biological mediators (gestation and birthweight) (HR 2.14; 95% CI 1.25,3.64). Similar associations were documented for post-perinatal deaths but for perinatal mortality the higher risk was not statistically significant (P >0.05). In older mothers, the increased mortality risk was not statistically significant (P >0.05) after adjustment for socio-economic confounders.Conclusion:
Young motherhood is associated with an increased risk of post-perinatal mortality and measures to prevent early childbearing should be strengthened.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Risk factors
Language:
English
Journal:
Indian Pediatr
Year:
2016
Type:
Article
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