Lymphocytotoxic antibodies in patients with systemic lupus erythematosus & their household contacts.
Article
in English
| IMSEAR
| ID: sea-17927
ABSTRACT
Twenty patients with systemic lupus erythematosus (SLE) and their 51 household contacts were screened for the presence of lymphocytotoxic antibodies. A high prevalence of lymphocytotoxic antibodies (LCTAB) was observed in the patients (80% against T cells and 100% against B cells). The antibodies carried specificity for HLA-B5/35 and HLA-DR2/DR3. A high prevalence of LCTAB was also observed in contacts (55% LCTAB-T cells, 88% LCTAB-B cells) with no difference being seen between consanguineous and non-consanguineous male or female relatives.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
B-Lymphocytes
/
T-Lymphocytes
/
Family
/
Adult
/
HLA Antigens
/
Lupus Erythematosus, Systemic
/
Antilymphocyte Serum
Language:
English
Year:
1990
Type:
Article
Similar
MEDLINE
...
LILACS
LIS