LDH Levels in Pregnancy and its Association with Severity of the Disease and Feto-maternal Outcome in Pre-eclampsia and Eclampsia.

ABSTRACT

Abstract The aim of present study was to correlate LDH levels in pregnant women and women with Preeclampsia and eclampsia in antepartum period and to study the correlation of maternal and perinatal outcome with LDH levels. Pregnant women in this study were enrolled in 3rd. trimester from 28 weeks onwards . Case control study was done in 100 women with normal B.P and in another 100 women having Pre-eclampsia and Eclampsia . Serum LDH level was measured using commercially available kits. Serum levels of LDH were significantly increased in women with Pre-eclampsia and eclampsia as compared to control group A significant positive correlation was found in patients with Pre-eclampsia and Eclampsia . LDH levels gradually increased with increase in the severity of the disease .. Regular monitoring of serum LDH levels in women with Pre-ecalmpsia and Eclampsia may help in detecting severity of the disease and associated end organ damage.