Calcium Polycarbophil in the Management of Fecal Incontinence.
Br J Med Med Res
;
2016; 12(9): 1-7
Article
in English
| IMSEAR
| ID: sea-182304
ABSTRACT
Background:
Few clinical studies have assessed the efficacy of calcium polycarbophil that is currently recommended as an ideal and initial bulk-forming agent in patients with fecal incontinence.Aims:
The aim of this study was to evaluate the short-term outcomes of calcium polycarbophil administration to patients with fecal incontinence due to a range of etiologies. StudyDesign:
This was a retrospective review of a single-institution experience.Methodology:
In total, 223 patients treated with calcium polycarbophil were enrolled. Efficacy measures included changes in the Cleveland Clinic Incontinence Score and the Bristol Stool Form Scale.Results:
Of the 223 patients who were enrolled, 195 were available for final analysis. Among the 195 patients, 15 (7.7%) experienced side effects; the most common side effects were constipation and hard stools. One month after the start of treatment, the mean Cleveland Clinic Incontinence Score decreased significantly compared with baseline (11.2±4.0 vs. 5.7±5.0, P = < .001). The mean stool consistency decreased significantly, with patients reporting more formed stools by the Bristol Stool Form Scale at 1 month than at baseline (4.4±1.5 vs. 3.9±1.1, P = < .001).Conclusions:
Our findings suggest that monotherapy with calcium polycarbophil appears to be a safe and beneficial approach in the management of fecal incontinence.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
Br J Med Med Res
Year:
2016
Type:
Article
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