Effect of Valethamate Bromide on the First Stage of Labor.

ABSTRACT

Objectives: This study was undertaken to evaluate the effect of intramuscular valethamate bromide on the duration of labor, rate of cervical dilatation and the effect of the drug on the mother and the fetus. Material and Methods: This was a prospective study conducted in Dept. of Obstetrics and Gynecology at ESIC MC-PGIMSR Bangalore involving 200 women with fullterm pregnancy in active labor. Group A received valethamate bromide intramuscular injection. Group B was control group. Results: There was no significant difference in the parity, mean age of patients and mean duration of gestation in both the groups. But, there was difference in the mode of delivery. Valethamate bromide caused significant decrease in the duration of cervical phase of labor as compared to control group. There was no statistically significant difference in the Apgar score of new borns, and there were no maternal and fetal side effects. Conclusion: Valethamate bromide can be used in the management of labor for reducing the duration of first stage of labor without any untoward effects on mother and fetus.