Leptin, the Mediator of Energy Reserve has Role in Fertility: A Review

ABSTRACT

Leptin, an adipocytokine was discovered in 1994 as putative hormone involved in appetite control acting at hypothalamic level. Since its discovery lot of work has been done over this novel molecule and in variety of physiological domains. Previously it was speculated that fertility, which is the basis of species progression has link with total body mass and energy. Leptin which is involved both in appetite regulation and reproductive process is thought to be have role in fertility regulation. Leptin is secreted from adipose tissue, which is marker of energy reserve of the body. In this review the role of leptin in regulation of fertility has been discussed.