Double Whammy the Great Switch and a Complex Endgame

ABSTRACT

In 1988 the world health assembly resolved to eradicate poliomyelitis.The Live attenuated oral polio vaccine was the captain against the fight to eradicate poliomyelitis.It had indeed many advantages in the fight to eradicate polio.But despite its many advantages it has a risk for occurrence of rare cases of paralytic poliomyelitis among immunologically normal OPV recipients and additional risk of emergence of Vaccine derived polio virus(VDPVs).Poliovirus being an RNA virus are notorious for mutation.India is a polio free country since 2011 however endemicity of its neighbours are a detterent against dropping guard.This article reviews the introduction of Bivalent oral polio vaccine instead of trivalent oral polio vaccine and rationale of addition of Inactivated Polio vaccine on the road to the—Endgame Strategy