Cardiac Magnetic Resonance Findings In Left Ventricle Non Compaction: A Monocentric Study

ABSTRACT

BACKGROUND:TheimpactofLVNCindilatedcardiomyopathyandleftventriclesystolicdysfunctionis controversial .METHODS: A retrospective study of 46 patients, over a period of 09 years between September 2009 and December 2018, performed in the cardiology department “B”, IBN SINA hospital, Rabat, Morocco. RESULTS: The mean age was 44 ± 16 years with extremes ranging from 10 years to 97 years. A slight predominance of male with 54% was observed. In TTE only 17,4% of patients had a suspected LVNC. The mean LVEDD was 68.6 ± 8.4 mm. The mean LVEDV was 223.1 ± 76.3 ml with a maximum of 443 ml and a minimum of 122 ml. The mean LVEF was 37.1 ± 12.7. Akinesia was observed in 28% of patients involving the infero-septal wall in 97% of cases. The non compaction was located in anterolateral wall was involved in 97.8 % of cases, and the inferoseptal wall was always spared. The median NC/C ratio was 2.8 [2.5-3], with extremes ranging from 2.3 to 5. LGE was present in 59 % of our patients; mostly located in the infero-septal. In multivariate analysis, NC/C ratio correlates significantly with the presence of LGE in the infero-lateral wall and the apex respectively (p 0.04 and p 0.002). NC / C ratio correlates with LVEF (OR 0.03, CI [0.01-0.04], p 0.02). CONCLUSION: This study shows the CMR profile of LVNC Moroccan patients. Our results affirm that the NC/C ratio in LVNC is a major determinant of LV fiosis and systolic dysfunction.