In Vitro Activity Of Colistin Against Multidrug Resistant Gram Negative Bacilli (MDR Gnb) Isolated From Various Clinical Specimens
Article
| IMSEAR
| ID: sea-184983
ABSTRACT
Introduction:
Currently colistin is increasingly being used against multidrug resistant gram negative bacteria which include Pseudomonas aeruginosa,,Acinetobacterbaumanii,Escherichia coli, Klebsiellapneumoniae& Salmonella enterica. [1] Colistin resistant organisms are reported in various parts of world.Methods:
Total 200 MDR GNB isolates were included in the study & tested for their susceptibility to colistin by Kirby Bauer Disc Diffusion Test.Results:
Isolates consisted of 64 Escherichia coli,45 Pseudomonas aeruginosa,44 Klebsiella pneumoniae,32 Citrobacter koseri,13 Acinetobacterbaumanii& 2 Proteus mirabilis. Of these, 69 (34.5%) were resistant to Colistin. Colistin resistance in highest number was detected in Escherichia coliisolates obtained from various samples.Conclusion:
As colistin resistance is emerging rapidly,measures are necessary to restrict indiscriminate use of antimicrobials& to adhere strictly to the hospital antibiotic policy. it is also the need of an hour that newer antimicrobials get discovered soon to tackle such MDR microorganisms.
Full text:
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Index:
IMSEAR (South-East Asia)
Year:
2018
Type:
Article
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