Clinico–Epidemiological Pattern Of Oral Lesion In Seropositive Patients : A Hospital Base Study

ABSTRACT

Background:Oral manifestations of HIVdisease is important, as they affect the quality of life and useful marker of disease progression . Aims:The study was designed to search for the oral lesions in seropositive patients and their possible prognostic value.Methods: This prospective observational study included 211 new cases withconsecutive two ELISAtest positive attended in OPD . Relevant investigations and biopsies were taken to confirm clinical diagnosis . The causal relationship between prevalence of oral lesions and demographical variants,therapeutic regimen and CD4 count were evaluated.The technique and protocol were approved by the ethics committee of the institution.Results:Out of 211 patients ,75 (35.44%) patients had detectable oral lesion with male predominance . Majority belonged to the age group of 21- 30 years . All the variants ofcandidiasis were seen. Pseudo membranous type was most frequently observed .Herpes simplex is the commonest viral infection. One case of hairy leukoplakia was seen. Necrotizing ulcerative periodontitis (NUP) was observed in four cases. Aphthous ulcer were seen in eight cases.Conclusions:In our series cases with orofacial involvement had CD4 count <600 cells/ml. Majority of the patients had CD4 < 200 cells/ml