Reducing Mortality & Hospital Stay In Swine Flu Patients With Early Diagnosis And Treatment With Oseltamivir And Iv Vitamin C- A Detailed Clinical Perspective.

ABSTRACT

–H1N1 INFECTION also known as Swine flu, is a viral illness seen in Humans. 2009 WHO declared a Pandemic as many people suffered worldwide. The clinical picture in severe cases of pandemic (H1N1) 2009 influenza is markedly different from the disease pattern seen during epidemics of seasonal influenza. [1] The dominant strain flu strain in India this year was the A/Michigan/7/2009 (H1N1) pdm09 virus, which replaced in 2016. A/California/7/2009 (H1N1) pdm09 virus as the predominant virus around the world. As per ICMR reports, A cross–sectional study on patients coming with flu like symptoms was carried out over a period of 12 months in a public hospital. Total 300 Patients were tested, 71 cases were admitted.43 were positive for H1N1. The Patients were categorised them into A, B, C as per National guidelines of WHO on H1N1 epidemics, they were divided in 2 Random groups. Group 1 was treated with Oseltamivir 75 mg Bid and Vitamin C 1500 mg IV/day. A reduced rate of complications of PCR POSITIVE H1N1 Michigan/7/2009/pdm09 H1N1, was observed. The average hospital stays remained 4 days as compared to 10 days in patients not given Vitamin C iv. No death was reported after discharge. Early administration of Vitamin C administration as adjuvant therapy with Oseltamivir, helped to reduce hospital stay, complications and Mortality