Vasomotion Changes After Hyperbaric Oxygen Therapy In Diabetic Patients

ABSTRACT

Backround Aim of this study was to assess changes in vasomotion during post–occlusive reactive hyperaemia in patients after hyperbaric oxygen therapy (HBOT). Methods: 38 patients with type 2 diabetes mellitus underwent 15 sessions of HBOT consisting of 90 minutes of eathing 100 % oxygen at 2.5 atm. We used laser Doppler flowmetry (LDF) to assess vasomotion during post–occlusive reactive hyperaemia. Results: We observed significant increase in endothelial (3.22 [2.07 – 5.31] vs. 4.91 [2.9 – 6.57], p < 0.05), neurogenic (0.64 [0.44 – 1.01] vs. 0.85 [0.53 – 1.63], p < 0.05), cardiac (9.22 [7.21 – 13.79] vs. 12.74 [8.66 – 16.83], p < 0.05) and total spectral activity (20.93 [15.97 – 27.88] vs. 27.96 [17.45 – 37.99], p < 0.05) after HBOT. No significant changes were observed in myogenic and respiratory spectral activity Conclusion: Our study demonstrated vasomotion changes measured by LDF after HBOT.