Global Longitudinal Strain Evaluation In Hypertension With And Without Left Ventricular Hypertrophy By Speckle Tracking Echocardiography

ABSTRACT

Aim:Assessment of Left ventricular (LV) function in hypertensive patients with left ventricular hypertrophy (LVH) and in those without LVH using two dimensional speckle tracking echocardiography (2D-STE).Materials and Methods:Hundred hypertensive patients were included in the study. Of these 50 patients with LVH and 50 patients with non LVH and all had normal left ventricular ejection fraction (LVEF). Two-dimensional conventional and speckle tracking echocardiography was done to all patients to assess left ventricle systolic function and global longitudinal strain.Results:There was no significant difference between hypertensive patients with LVH and without LVH regarding age and sex distribution. There was significantly higher septal wall thickness (1.2±0.3cm p= <0.001), Posterior wall thickness (1.3±0.4cm p=<0.001), and left atrium size (3.9±0.5) in hypertensive patients with LVH (P< 0.001) compared to non LVH patients. GLS (Global Longitudinal Strain) was significantly decreased in patients with systemic hypertension with LVH (−17.4 ± 3.03) compared to no LVH (-19.6±4.6) patients (Pvalue =0.005).Conclusion:This study concluded that there is impairment of left ventricular (LV) systolic function detected by two-dimensional speckle tracking echocardiography in hypertensive patients, especially if associated with LVH with apparently preserved LVsystolic function