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Furosemide: Would it help to improve the lungs as evaluated by sonography and compliance during aortic coarctation surgery
Ann Card Anaesth ; 2019 Jul; 22(3): 254-259
Article | IMSEAR | ID: sea-185843
ABSTRACT

Background:

We evaluated furosemide on attenuating lung injury and/or edema during coarctation repair surgery. We evaluated dynamic lung compliance. We measured the degree of lung edema by means of lung ultrasound (LUS). We recorded the (PaO2/FiO2ratio) as an indicator for oxygenation. Materials and

Methods:

A study was conducted on 56 patients. Patients were divided into two groups control group (Group C) which did not receive furosemide and furosemide group (Group F) at a dose of 1 mg/kg at induction of anesthesia. Dynamic lung compliance was calculated at induction (Cdyn 1) and at the end of the surgery (Cdyn 2). The (PaO2/FiO2ratio) was calculated at start and end of surgery as (PF 1) and (PF 2), respectively. LUS was performed after induction (LUS 1) and at the end of the surgery. LUS 2 using the 12 regions method plotting the results on scale from 0 to 36. Mechanical ventilation days were recorded.

Results:

Administering furosemide attenuated the lung injury/edema and other pulmonary complications. Furosemide administration improved the dynamic lung compliance in the F Group compared to the C Group. Furthermore, it increased the (PaO2/FiO2ratio) in the F Group compared to the C Group. LUS scale values were lower in the F Group compared to the C Group. There was also less postoperative mechanical ventilation days.

Conclusions:

The use of furosemide was accompanied by improved lung injury/edema profile as indicated by a much less drop in dynamic lung compliance, better oxygenation, a more favorable LUS scale with less parenchymal lung affection.

Full text: Available Index: IMSEAR (South-East Asia) Journal: Ann Card Anaesth Year: 2019 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Journal: Ann Card Anaesth Year: 2019 Type: Article