Correlation of Thyroid Hormones with FSH, LH and Prolactin in Infertility in the Reproductive Age Group Women

ABSTRACT

Introduction: Measurement of prolactin and thyroid hormones, especially thyroid stimulating hormone (TSH), has been considered an important component of infertility work up in women. Thyroid dysfunctions interfere with numerous aspects of reproduction and pregnancy. Aim: To correlate thyroid hormones level with FSH, LH and prolactin in infertility in the reproductive age group women. Materials and methods: This study includes 100 infertile women who attended infertility clinic of our institute along with 50 fertile women as a control group between age group of 20 to 40 years. Out of 100 infertile women, 70 were of primary infertility and 30 of secondary infertility. Thyroid hormones and infertility hormones level is measured from all participants by chemiluminance immunoassay. Results: Prolactin and TSH were positively correlated with each other. They were also negatively correlated with LH, FSH and T3 in infertile groups. Therefore we can say that hyperprolactinemia and hypothyroidism plays key role in etiopathogenesis of infertility. Conclusion: There was a higher crude prevalence of hypothyroidism and hyperprolactinemia in the infertile women as compared to the fertile ones in the control group.