A comparative assessment of thyroid hormones and lipid profile among hypothyroid patients: A hospital based case control study

ABSTRACT

Background: In India, thyroid disorders are the most common among all the endocrine disorders and hypothyroidism being more common than hyperthyroid state and carcinoma. Bandi A, Pyadala N, Srivani N, Borugadda R, Maity SN, Ravi Kumar BN, Polavarapu R. A comparative assessment of thyroid hormones and lipid profile among hypothyroid patients A hospital based case control study. IAIM, 2016; 3(9) 108- 114. Page 109 Objectives: The present study was undertaken to assess the association of dyslipidemia in hypothyroid patients. Materials and methods: A total of 50 study subjects of both gender groups were selected from the medicine ward of Maheshwara Hospital during the period from January 2016 to April 2016. Fasting venous blood sample were analysed for Thyroid hormones like, T3, T4, TSH and lipid profile. Statistical analysis was done using student unpaired t test. Result: The thyroid stimulating hormone (TSH) and total cholesterol, LDL, VLDL values were significantly higher, whereas T3, T4 and HDL values were in a decreasing order with that of control group. Conclusion: The present study concludes that hypothyroidism is associated with dyslipidemia having raise in all lipid parameters, which may increase the risk of cardiovascular diseases. Finally regular assessment of thyroid hormones and lipid profile among hypothyroid patients can prevent progression of the disease to severity