Ovarian tumors – Incidence and histopathological spectrum in tertiary care center, Valsad

ABSTRACT

Introduction: Ovarian tumors are now the one of the leading cause of death involving a wide spectrum of clinical, morphological and histopathological diagnosis. It frequently does not result in symptoms until the tumor has spread extensively and pose difficulties to clinicians. Objectives: The aim was to study the incidence and histopathological spectrum of ovarian tumors according to WHO classification in different age group and its clinical correlation. Materials and methods: A study was undertaken during a period of May 2011 to December 2017. The tumors were classified according to WHO classification after thorough examination of H&E slides. Data of clinical presentation of patient was also recorded in each case. Results: There were total 162 cases were studied, amongst which surface epithelial tumors were the commonest variety accounting for 126(77.7%) cases, followed by Germ cell tumors 30(18.5%) cases and Sex-cord stromal tumors 6(3.8%) cases. Benign tumors (93.2%) were more common than malignant (6.2%) and borderline (0.6%). Among benign tumors, serous cystadenoma (57.4%) were the most common followed by mucinous cystadenoma (16%) and mature teratoma (16%). Most of the ovarian tumors were unilateral (89.5%) with left sided predominance (49.4%). Majority of benign tumors presented with cystic consistency (67.9%) and mixed consistency (4.3%) in malignant tumors. The age range was 4 year to 70 years. Abdominal pain (48.8%) was the commonest clinical presentation. Conclusion: Ovarian tumors were found to occur in wide range of age with bimodal peak for malignant tumors. Benign tumors were more common across the all age group. An accurate histopathological diagnosis and staging is important for therapeutic and prognostic purpose.