Leuprolide Vs triptorelin: The recent trends in GnRH analogues in precocious puberty

ABSTRACT

Precocious puberty resulting from hypothalamic-pitiutary-gonadal axis activation is increasing problem in children and early institution of therapy for the axis suppression allows the patients to attain target adult heights. The review evaluates and compares the efficacy of the most commonly used two GnRH analogues leuprolide and triptorelin; and the recent trends in their dosages.