Long†term results after treatment of periodontitis in patients with Papillon Lefevre syndrome with or without antibiotics a comparative study

ABSTRACT

Aim: Evaluation of periodontal status in patients with Papillon–Lefèvre syndrome (PLS) observed for ≥5 years, Treatment of patients of PLS with SRP and maintenance for a period of ≥5 years, Comparing the effects of treatment of periodontitis in (PLS) patients with SRP (scaling and root planning) as a monotherapy with antibiotics as an adjunct. Materials and methods: All subject showing signs and symptoms of PLS, were selected for this study comprising of both the sexes, visiting outpatient Department of Periodontology, Govt. Dental College and Hospital Srinagar. Eight patients (aged 5-12 years) from five families (three pairs of siblings) were included. Subjects were randomly distributed into two groups 4 patients each. Control group- Group A given SRP + Placebo and Treatment group- Group B given SRP + 250 mg of amoxicillin TDS and 125 clavulanate for 14 days and metronidazole 250 mg BD for 14 days . Results: In this study by comprehensive maintenance therapy in both the groups we delay the loss of dentition of the patients of PLS. The use of antibiotics had proven to show a statistically significant difference in retaining the teeth of PLS. Patients compared to the control. Conclusion: PLS patients, periodontitis may be arrested by combined mechanical and antibiotic periodontal treatment; extraction of severely diseased teeth; oral hygiene instructions; intensive maintenance therapy; and microbiological monitoring and treatment of the infection with Aggregatibacter actinomycetemcomitans.