A comparative study between the efficacy of fentanyl with bupivacaine 05% and buprenorphine with bupivacaine 05% for lower abdominal and lower limb surgeries in a Government Tertiary Care Teaching Hospital

ABSTRACT

Background: Pain is one of the most common and uncomfortable consequences of surgery, feared by all. Effective and rapid relief from pain is always a challenge but is necessary for alleviating nocioception – induced responses like endocrine-metabolic responses to surgery, autonomic reflexes with adverse effects on organ function, reflexes leading to muscle spasm, and other undesirable results. Aim of the study This study was done to compare the efficacy of intrathecal fentanyl with bupivacaine and buprenorphine with bupivacaine for all lower abdominal and lower limb surgeries. Materials and methods: Totally 60 ASA I and II patients of both sexes for different lower abdominal and lower limb surgeries were chosen for the study and the patients were divided into two groups of 30 patients in each group. Group F received 3 ml of 0.5% hyperbaric bupivacaine with 25 mcg fentanyl and group B received 3 ml of 0.5% hyperbaric bupivacaine with 75 mcg of buprenorphine. In our study, the time taken to achieve T10 level of the sensory blockade was considered as the time of V. Muruganantham, Nalini, Naheed Azar. A comparative study between the efficacy of fentanyl with bupivacaine 0.5% and buprenorphine with bupivacaine 0.5% for lower abdominal and lower limb surgeries in a Government Tertiary Care Teaching Hospital. IAIM, 2019; 6(5) 80-86. Page 81 onset of sensory block tested with pinprick method, motor block assessed by the onset of Bromage scale 3 and it was found that onset of the sensory block with bupivacaine + Fentanyl was earlier than compared with bupivacaine + Buprenorphine. Results: In the postoperative period VAS scores were significantly low for the buprenorphine group (Group B) when compared with fentanyl group (Group F). Conclusion: To summarize buprenorphine has higher efficacy with intrathecal bupivacaine, prolonged duration of postoperative analgesia and also analgesic-sparing effect in the post-operative period when compared to fentanyl.