A Comparative Study of Diagnostic Accuracy of DCMRI Vs Mammography in Detecting Female Breast Cancer

ABSTRACT

Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers with an estimated 1.67 million new cancer cases diagnosed in 2012.This study was designed with the primary aim to compare the difference between MRI and Mammography in patients presenting with breast related complaints. Methods: This prospective study was conducted between Oct 2006 and Feb 2008 in the department of Radio diagnosis & Imaging at Army Hospital (Research & Referral), Delhi Cantt. Fifty patients screened with suspicious malignant breast lesions were taken up for the study. Results: Mammography Imaging revealed that most of the malignant masses were found to have architectural distortion & calcification with fewer cases of skin involvement, PI& Nipple retraction respectively. Benign masses were diagnosed with comparatively fewer cases of calcification and presence of other morphological features was rare. Various Imaging techniques have been compared with the Histopathology gold standard technique, When compared with USG Our study showed the sensitivity, specificity, PPV,NPV& Accuracy 67%,75%,80%,72%. Conclusion: Mammography compared to DCMRI has shown to produce false negative results, especially showing less sensitivity for diagnosis of breast cancer in younger women having dense breast