Assessment of Diagnostic Efficiency of Pipelle Endometrial Sampling in Patients with Abnormal Uterine Bleeding

ABSTRACT

Abnormal uterine bleeding is among the most prevalent uterine disorders among the females of pre and perimenopausal age. Endometrial sampling pipelle method is emerging as convenient and popular method for endometrial sampling in recent scenario. Accuracy of pipelle method in comparison of dilatation & curettage is still not clear. Therefore the present study was designed to assess the efficacy of pipelle method in comparison of dilatation & curettage method for endometrial sampling in patients with abnormal uterine bleeding. Methods: The present study included 200 patients suffering with abnormal uterine bleeding. On the other hand, patients having abnormal uterine bleeding of 16 to 70 years age having normal haematological findings were included in the study. Pippele method of sampling was performed before the D & C method was completed in all the patients. Results: Histological findings of the endometrial obtained by pipellle method showed endometrial hyperplasia (44%) was most common followed by proliferative phase (16%), secretary phase (12%) and proliferative endometrial phase (12%). While, endometrial carcinoma and choriocarcinoma were recorded in 2.5% and 1% cases. On the other hand, proliferative phase, secretary phase, endometrial phase and proliferative endometrial phase were observed in 17.5%, 13%, 39.5% and 15% correspondingly. Endometrial carcinoma and choriocarcinoma detected in 4% and 1.5% patients. Conclusion: Results of the present study showed that pipelle method of endometrial sampling is equally effective to its contemporary method D & C. Moreover, this technique is more convenient as it can be performed outdoor during routine examination. In addition there is no need of anaesthesia for pipelle method like D & C. We strongly recommend pippele method instead of D & C for the diagnosis of abnormal uterine bleeding as it has a high specificity rate and accuracy rate, without post sampling bleeding and pain.