Role of Biochemical Parameters and GFR as Prognostification Factors in PUV Patients

ABSTRACT

Posterior urethral valves (PUV) are the most common cause of lower urinary tract obstruction in the male child with broad spectrum of clinical presentation, disease severity and associated sequelae. Methods: Baseline investigations included pre fulguration blood renal profile, radiological (DTPA) investigation followed by post fulguration blood renal profile and radiological investigation. The outcome has been studied by the analysis of the biochemical markers & GFR & statistical tests shall be applied where ever necessary Improvement in quality of life in terms of dribbling, enuresis, pant wetting, school dropouts, growth & development. Results: The mean urea, Hb and creatinine level at different interval was non- significant (P> 0.05). The most common case of USG was B/l HDN (5) and B/L hydronephrosis (5). Conclusion: Aggressive surgical treatment is better policy to treat the patients with PUV. Urine cultures should be done in the follow up of PUV patients to prevent the recurrent UTI as it adversely effects the kidneys.