Comparison of the Effectiveness of Topical Podophyllin, Cryotherapy, CO2 Laser and Cryotherapy + CO2 Laser in Condyloma Acuminata in Females

ABSTRACT

Condyloma acuminata, the most common sexually transmitted viral disease of genitalia is caused by Human Papilloma Virus (HPV). Methods: The present work was designed as a randomized interventional study during the period from November 2016 to October 2017. Results: A total of 80 non pregnant sexually active female patients were included in the study. In this study the mean age of the patients was 23 years. Out of total 80 patients, 67 had affected partners. The mean duration of complete clearance was 3.6 weeks for podophyllin, 4.8 weeks for cryotherapy, 2 weeks for C02 laser and 1.8 weeks for CO2 laser + cryotherapy. In CO2 + cryo group, complete clearance was seen in all 20 lesions, in CO2 alone group 17 lesions, cryo alone showed complete clearance in 13 patients and in podophyllin group the number was 15. Conclusion: This study shows that CO2 laser + cryotherapy is most effective treatment followed by CO2 laser alone and podophyllin.