Evaluation of Hydrolytic Enzymes among Smokers with Chronic Periodontitis

ABSTRACT

This study was done to evaluate the level of hydrolytic enzymes ALP and ACP in GCFamong chronic periodontitis patients with smoking habit. Methods: A total of 80 subjects were selected for the study. The study population was further divided into 4 group (Group 1 – clinically healthy periodontium, group – 2 gingivitis, group – 3 periodontitis, group - 4 smokers with periodontitis ). Based on clinical assessment of probing depth , bleeding on probing and radiographic evaluation of alveolar bone loss, GCF samples were taken to assess the level of enzymes. Results: Obtained results shows statistically significant increase in the level of ALP activity in GCF from periodontitis patients with smoking habit. There was positive correlation between the activity of examined GCF enzymes and values of the plaque index, gingival index and periodontal disease index. Conclusion: Based on these results, it can be assume that ALP activity in GCF may be used as potent biochemical markers for periodontal destruction.