Dosimetric Comparison of IMRT and Rapid ARC for High Grade Gliomas

ABSTRACT

High grade gliomas are common intracranial tumors and adjuvant radiotherapy after maximal safe surgical resection is the cornerstone of the management. Aim: The aim of the present study was to compare the dose distribution characteristics in patients with high grade gliomas planned with Intensity-modulated radiotherapy (IMRT) and Rapid Arc (RA). Methods: Two plan sets by IMRT and RA were generated for each patient on planning Computed Tomography (CT) data sets and were then compared. Results: Total dose prescribed was 60 Gy given in biphasic manner as per Radiation Therapy Oncology Group (RTOG) guidelines guidelines. Planning Target Volume (PTV) coverage (mean values) for IMRT was found 98% and 96% for RA. Conformity Index (CI) was 1.3 for RA, 1.2 for IMRT. Homogeneity Index (HI) was found to be 1.03 for IMRT, 1.04 for RA. Dose maximum (Dmax) for the PTV was equal for IMRT and RA (106%). Conclusions: The dose to Organ at Risks (OARs) was within the acceptable limits and comparable in both the techniques, however RA augments shorter treatment time.