Solitary Fibrous Tumour of Liver: A Case Report and Literature Review

ABSTRACT

Solitary fibrous tumour is an uncommon mesenchymal neoplasm diagnosis of which is difficult because of non-specific clinical and radiological features. A 76 year old male presented with complaints of nausea and vomiting. Physical examination revealed firm mass in the right hypochondrium and epigastrium. CT scan revealed a heterogeneous, lobed and some vascularized mass of size 17.6 x 12.8 cm, situated in the right lobe. After surgery the mass was found to measure 19 cm x 13 cm x 10 cm. Histopathological examination found the tumour cells to be strongly positive for vimentin and CD34, confirming our diagnosis. Microscopic examination revealed haphazard arrangement of spindle cells and collagen bundles between the tumour cells with mild nuclear pleomorphism, and the mitotic count was 0-1/10 high power field. The post-operative course was uncomplicated and the patient was discharged home. After 16 months of follow up examinations, there was no recurrence of disease, local or distant metastasis and the patient remained asymptomatic. The clinical presentation and the radiological imaging can be very non-specific. Suggestive features on CT scan are a single, large, well-circumscribed, heterogeneously enhancing hepatic mass.