Gentamicin Loaded Bone Cement as Root End & Bone Defect Filling Material In Apical Resurgery Cases; A Clinical Study

ABSTRACT

Aim: Antibiotic loaded bone cement has been used extensively in orthopaedic surgery and in the treatment of osseous defects resulting from joint infection, osteomyelitis, osteitis. No endodontic investigation has used this type of material in the treatment of bony resorptive defects of the periapical lesions associated with failed endodontic therapy or periapical surgery. Therefore, this study was conducted with the use of gentamycin loaded bone cement, to assess healing ability of osseous defects in apical re-surgery cases after failed apical surgery. Methods: In all patients periapical lesions were surgically removed and gentamicin loaded bone cement was used as root end filling material and then carefully packed without pressure into the bony defect. Results: Long-term recall demonstrated clinical and radiographic healing and good tolerance of bone fill material by the periapical tissues. Conclusion: results from this study shows that gentamicin loaded bone cement is a biocompatible material and can be used effectively in apical resurgery cases for treating recalcitrant infectious osseous defects of periapical lesions associated with failed periapical surgery.