Sickle cell anemia: An update on diagnosis, management and prevention strategies
Article
| IMSEAR
| ID: sea-191821
ABSTRACT
Sickle cell anemia is the most common disease entity of all the monogenic disorders. This is an autosomal recessive disorder. HbS polymerization, vaso-occlusion, and hemolytic anemia are central to the pathophysiology of sickle cell disease, they precipitate a cascade of pathologic events, which in turn lead to a wide range of complications. The disease is particularly more prevalent in certain regions of the country like Odisha, Madhya Pradesh, Tamilnadu and has a significant impact on morbidity. Community based approach by providing availability of screening tests, & pre-marital and pre-pregnancy counselling should be initiated to reduce the disease burden in the society.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Diagnostic study
Year:
2018
Type:
Article
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