Effect of arteether alpha/beta on uncomplicated falciparum malaria cases in Upper Assam.
Article
in English
| IMSEAR
| ID: sea-19203
ABSTRACT
Thirty patients of uncomplicated Plasmodium falciparum malaria completed a clinical trial of arteether alpha/beta conducted in a malaria endemic tea garden of district Dibrugarh, Assam. Arteether was given intramuscularly in once a day dose of 150 mg for three consecutive days. The cure rate was 100 per cent with mean fever and parasite clearance time of 42.4 +/- 17.5 and 37.6 +/- 13.6 h respectively. Recrudescence/reinfection rate was 6.7 per cent. Palpable spleens of twenty out of twenty one cases on day 0 became non palpable within 28 days. Following the treatment, percentage of hemoglobin improved marginally with no remarkable change in total and differential leucocyte count. Arteether alpha/beta, besides being a potent and fast acting schizontocidal drug, also exhibited gametocytocidal action on P. falciparum.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sesquiterpenes
/
Female
/
Humans
/
Male
/
Adolescent
/
Malaria, Falciparum
/
Adult
/
Artemisinins
/
India
/
Middle Aged
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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