Successful treatment of metastatic extramammary Paget's disease with pemetrexed monotherapy systemically and 5-fluorouracil topically
Indian J Dermatol Venereol Leprol
;
2019 Jan; 85(1): 56-59
Article
| IMSEAR
| ID: sea-192438
ABSTRACT
Advanced extramammary Paget's disease does not have a standardized treatment guideline as its incidence is low and has been rarely reported in literature. Here we describe a case of metastatic extramammary Paget's disease successfully treated with topical 5-fluorouracil (5-FU) and systemic pemetrexed. The therapy was safe without any appreciable adverse effects like diarrhea, rash, neutropenia or fatigue; maintaining remission for more than 6 months. Thus, we propose 5-FU and pemetrexed as the first-line therapy for advanced extramammary Paget's disease, especially for aged patients with unresectable skin lesions.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Practice guideline
Journal:
Indian J Dermatol Venereol Leprol
Year:
2019
Type:
Article
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