The Coagulation Profile on Pregnancy Induced Hypertensive Patients in Third Trimester of Pregnancy – The Prospective and Observational Study

ABSTRACT

Background:Hypertensive disorders are the most important cause of maternal and perinatal morbidity and mortality. The aim of present study is to know the changes in certain parameters of coagulation profile in pregnancy induced hypertensive patients in third trimester of pregnancy, so that treatment can be planned to reduce maternal morbidity and mortality. Methods: The study was undertaken at Department of Obstetrics and Gynecology, NIMS Medical College and Hospital, Rajasthan for the period of 1 year on 100 patients diagnosed with PIH. Result: Mean BT, CT were in normal range in all patients of PIH; but CT was significantly higher in E group than PE >N. Mean CRT was poor in patients with E group and normal in patients of PE & GTN group. Mean platelet counts & serum fibrinogen levels found to be decreased with severity of PIH. Prolonged mean PT & aPTT were observed in patients with E. Conclusion: Inclusion of coagulation profile with routine investigations leads to early prediction of severity of PIH and subsequent complications.