Assessment of Protein C and Protein S of Pregnancy Loss Victims
Article
| IMSEAR
| ID: sea-192784
ABSTRACT
Background:
The haemostatic changes that result in thrombophilia during the pregnant state have been linked to pregnancy loss.Objective:
Assessment of Protein S, and Protein C assays in pregnancy loss victims in Abia State, South East, Nigeria. Materials andMethods:
This was a cross-sectional study involving women in their reproductive years. Study population was stratified into 3 groups and the Protein C and Protein S concentrations measured and compared among the three groups.Results:
A total of 130 apparently healthy Nigerian women of child-bearing age were enrolled in the study. The study groups consisted of 70 women who had just lost a pregnancy, 30 women with normally progressing pregnancy and 30 nonpregnant women. The protein C concentration for the pregnancy-loss subjects was significantly lower than that of the normal pregnancy at p ? 0.01 while that of Protein S showed non-significance (p > 0.05).Conclusion:
Protein C deficiency is associated with increase in pregnancy loss.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Observational study
/
Risk factors
Year:
2019
Type:
Article
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