Correlation between serum magnesium levels and diabetic retinopathy in type 2 diabetes mellitus

ABSTRACT

Background: In this study, an attempt has been made to find the correlation between Diabetic Retinopathy (DR) and serum magnesium in type 2 Diabetic Mellitus (DM) cases.Methods: Study was conducted in the department of General Medicine, GSL Medical College. Study protocol was approved by institutional ethical committee. All the non-critically ill type 2 DM individuals of all ages attended the outpatient services were included in the study. The reference range of Magnesium was taken as 1.7-2.4 mg/dL. Patients with low and normal Magnesium levels were categorized as cases and controls respectively. Statistical analysis was performed using SPSS software 21, Chi square test was used to compare the different qualitative variables; p<0.05 was considered as statistically significant.Results: A total of 163 individuals were included in the study, the mean age was 55.72 years, ranged between 39 to 75 years; male female ratio was 1.12. DR was diagnosed in 54% cases and low magnesium levels were detected in 40% cases; the difference was statistically not significant (p>0.05).Conclusions: Estimation of glycaemic levels and serum magnesium can help us predict the onset and progression of DR.