Sexual Dimorphism In Splenial Morphology: A Cadaveric Study

ABSTRACT

Introduction: There is no uniformity in published works regarding the presence of sexual dimorphism in themorphology of the Corpus Callosum (CC), specifically splenium.Objective: The present study was conducted on formalin fixed preserved brains to get comprehensive dataregarding gender related differences of CC.Materials and Methods: 50 formalin fixed human brains without apparent neuropathology were cut in themidsagittal plane. The various morphometric features of CC were measured and recorded on these midsagittalsections.The diameters measured were (i) length of CC (AB), (ii) Width of body of CC at mid point (WBM), (iii) Maximumwidth of genu (AE), (iv) Maximum width of splenium (BD).Results: Mean values of two parameters (AB and AE) were greater in male than in female. However, 2 parameters(WMB and BD) had greater value in female than male. Only two parameters (AB and BD) showed statisticallysignificant (p value < 0.05) gender differences.Conclusion:significant sexual dimorphism was observed in the longitudinal length of the CC, including morphologyof the splenium. However, these gender related differences are more likely due to individual differences regardlessof sex