Institutional outbreak of varicella in a child welfare institute in Chandigarh, North India
Indian J Med Microbiol
;
2019 Mar; 37(1): 24-28
Article
| IMSEAR
| ID: sea-198855
ABSTRACT
Introduction:
Varicella outbreaks are known to occur in developing nations as vaccine coverage is still low. Material andMethods:
In the present study, an institutional outbreak from Chandigarh, India, is reported wherein the utility of non-invasive samples such as saliva and urine was studied for the molecular diagnosis of varicella by conventional polymerase chain reaction (PCR), real-time PCR and real-time loop-mediated isothermal amplification (real-time LAMP).Results:
The results of the present study showed that saliva and urine samples can be used for outbreak investigation of varicella compared to varicella-zoster virus DNA in vesicular swab samples with reasonable sensitivity.Conclusion:
Thus, molecular techniques may be useful in the early identification of the outbreak and timely isolation, and the treatment of cases can further prevent its spread.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2019
Type:
Article
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