Detection of cytomegalovirus disease by real-time quantitative PCR targeting immediate early gene (ppUL83) in different samples among post-renal-transplant recipients
Indian J Med Microbiol
;
2019 Jun; 37(2): 281-284
Article
| IMSEAR
| ID: sea-198873
ABSTRACT
Renal transplantation is a treatment option for end-stage renal disease (ESRD). Cytomegalovirus (CMV) infection was analysed among symptomatic and asymptomatic post-renal-transplant recipients (PRTRs). A total of 30 PRTRs were enrolled. DNA was extracted and quantitative real-time PCR for CMV (CMV R-Gene, France) targeting ppUL83 gene was performed on whole blood, urine and saliva. The detection rate of CMV was found to be 27% (n = 8) in different samples, including whole blood, urine and saliva. Among 30 PRTRs, 53% (n = 16) of the PRTRs did not shed virus in saliva. About 7% of CMV was detected only in saliva among PRTRs who were symptomatic.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Diagnostic study
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2019
Type:
Article
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