Encephalitic presentation of Neonatal Chikungunya: A Case Series

ABSTRACT

Objective: To describe clinical features and early neurological outcomes in neonatalChikungunya. Methods: Clinical, pathological and radiological details of neonates with acuteencephalitic features and typical rash, later diagnosed as Chikungunya, are presented.Neurodevelopmental evaluation and imaging was done at discharge/three months. Results:Abnormal neurological examination with fever was typical presentation in all 13 babies with/without seizures/peri-oral rashes; 12 had persistent neurological abnormalities at discharge.A follow-up at three months revealed continued neurodevelopmental deficits. Neuroimagingabnormalities were seen in eight out of ten cases. Conclusions: Perinatal Chikungunyashould be considered in neonates presenting within first week with fever, encephalopathy andperioral rashes with/without seizures with history of maternal Chikungunya within last weekbefore delivery.