Bone Mineral Content and Density in Indian Children with Congenital Adrenal Hyperplasia

ABSTRACT

Objective: To study the bone mineral content and density in children with congenital adrenalhyperplasia (CAH). Methods: 35 children with congenital adrenal hyperplasia and 35 healthycontrols. Bone mineral content and density were studied by Dual Energy X-rayabsorptiometry. Results: The mean (SD) of lumbar spine bone mineral density (g/cm2) [0.590(0.100) vs 0.589 (0.088) (P=0.97)], total Body less head bone mineral density (g/cm2) [0.536(0.090) vs 0.548 (0.111) (P=0.64)], lumbar spine bone mineral content (g) [29.85 (27.63) vs31.03 (29.19) (P=0.86)], and total body less head bone mineral content (g) [254.27 (281.25)vs 273.07 (330.71) (P=0.79)] were not different between children with CAH and controls,respectively. Conclusion: Bone mineral density and content in children with congenitaladrenal hyperplasia are maintained in the normal range.