Comparison of Soybean-based Oil and MCT-olive-fish-soy Oil Intravenous Lipid Emulsions on Soluble Adhesion Markers in Preterm Neonates with Sepsis: A Randomized Controlled Trial
Indian Pediatr
;
2019 Oct; 56(10): 841-844
Article
| IMSEAR
| ID: sea-199402
ABSTRACT
Objectives:
To compare the effects of two different intravenous lipid emulsions on solubleadhesion markers in preterm infants with sepsis.Methods:
This randomized controlled pilottrial was conducted from February 2016 to February 2017. 40 preterm infants with sepsiswere enrolled and assigned to receive either Medium chain triglyceride-Olive-Fish-Soy lipidemulsion (MOFS-LE) or soybean oil-based lipid emulsion (S-LE). Outcomes of the studywere changes in sICAM-1 and leukocyte integrin β2 levels, and growth after 7 days ofintervention.Results:
Leukocyte integrin β2 was significantly higher in MOFS-LE group. Nostatistically significant differences were observed for sICAM-1, duration of mechanicalventilation and antibiotics treatment, and mortality rate.Conclusions:
Leukocyte integrin β2was significantly higher in preterm septic neonates who received MOFS-LE
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Controlled clinical trial
Journal:
Indian Pediatr
Year:
2019
Type:
Article
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