Effect of Different Doses of Inhaled Corticosteroids on the Isolation of Nasopharyngeal Flora in Children with Asthma
Indian Pediatr
;
2019 Nov; 56(11): 913-916
Article
| IMSEAR
| ID: sea-199420
ABSTRACT
Objectives:
To find the effects of inhaled corticosteroids and the impact of different doses ofinhaled corticosteroids on the isolation of nasopharyngeal flora in asthmatic children aged 1-15 years.Methods:
The study included 75 children with asthma and 25 age-matchedcontrols. Nasopharyngeal swabs were obtained. Bacteria were identified by standardtechniques.Results:
Pathogenic organisms were isolated from 36% of asthmatic childrenand 20% of controls, the difference was not significant statistically (OR=2.25, 95% CI=0.75-6.67, P=0.13). There was no statistically significant association of using a high dose ofinhaled corticosteroids with the isolation of pathogenic organisms. Usage of biomass fuel forcooking in the household of asthmatic children increases the risk of colonization (OR=3.4,95% CI= 1.26-9.10, P=0.03).Conclusion:
Inhaled corticosteroids are safe in the treatmentof asthma and there is no association between different doses of Inhaled corticosteroids andisolation of the pathogenic organism.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Journal:
Indian Pediatr
Year:
2019
Type:
Article
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