Comparison of Nepafenac Plus Steroid Versus Steroid Alone for Control of Ocular Inflammation after Phacoemulsification

ABSTRACT

Introduction: Cataract is the most common surgicalprocedure. Study was done to compare the effect of nepafenac0.1% plus prednisolone 1% vs prednisolone 1% alone incontrolling ocular inflammation after phacoemulsificationMaterial and Methods: A total of 140 patients wererandomized to receive prednisolone 1% (group I) vsnepafenac plus prednisolone 1% (group II) after uneventfulphacoemulsification. Patients were examined on first day,one week and one month for vision, slit lamp evaluation foranterior segment inflammation and cystoid macular edema.Results: Average visual acuity was 6/9 in both groups.Anterior segment inflammation was significantly less in groupII on first post operative day. On later visits, there was nosignificant difference in inflammation in both groups. CMEwas not seen in any group.Conclusion: This study suggests that addition of nepafenac0.1% to prednisolone 1% significantly reduces the intraocularinflammation after phacoemulsification in the earlypostoperative period.